Request PDF on ResearchGate | Beyond the 12/23 Rule of VDJ Recombination Independent of the Rag Proteins | The combinatorial repertoire of AgRs is established through somatic recombination of V, D. Following what is known as the 12/23 Rule, gene segments to be recombined are usually adjacent to RSSs of different spacer lengths (i.e., one has a "12RSS" and one has a "23RSS"). This is an important feature in the regulation of V(D)J recombination. Process. The RAG1/RAG2 enzyme complex follows the rule when joining V, D, and J segments, pairing bp spacer RSSs to bp spacer RSSs. This prevents two different genes coding for the same region from recombining (ex. V-V recombination).
VDJ recombination overview, time: 11:13Tags:Nokia e72 mobile cricket game,Bizzy body remix by p square testimony,Aplikasi al-quran untuk pc,File php stack overflow c++